There are a few holiday houses on Antiparos, but there is nothing else on Despotiko apart from a chapel and an archaeological site.
the depth of the passage between Tsimintri Island and Despotiko is 2 metre. Although some sailing yachts use this exit you better approach from the south.
Anchor: the best anchorage is in the back end of the bay on 3 - 4 metre. Really a very nice bay to stay, hardly waves and the wind is not as gusty as in other bays.